Hoʻokomo ʻo BOC Science i kahi kahua hou o ka XDC Bioconjugation Platform e holomua i ka noiʻi biomedical

ʻO BOC Sciences, kahi alakaʻi alakaʻi o nā kemika noiʻi a me nā lawelawe maʻamau, i hoʻolauna i kāna XDC bioconjugation platform hou, e hāʻawi ana i kahi mea hana nui no ka lawe ʻana i ka lāʻau.

ʻO ka papahana bioconjugation XDC hou i hāʻawi ʻia e BOC Science e hoʻolauna i kahi ʻano o nā ʻenehana holomua a me nā protocol i hoʻopaʻa ʻia, e hoʻololi i ke kaʻina hana o ka hoʻopili ʻana i nā pūhui i nā biomolecules.

Ma o ka leveraging state-of-the-art conjugation method, targeting drug delivery solutions and RNAi delivery system, hiki i nā kānaka ʻepekema ke loaʻa ka mana ʻike ʻole ma luna o ka hoʻolālā a me ka synthesis o bioconjugates.

Nā ʻano hoʻohui ʻia ʻO nā ʻano hana bioconjugation kuʻuna he mau hemahema, e like me ka mea ʻawaʻawa ʻole, hoʻemi ʻia ka paʻa o ka hui ʻana, a me ka nalowale o ka hana olaola. No ka hoʻoponopono ʻana i kēia mau palena, hoʻohana ʻo BOC Sciences 'XDC bioconjugation platform i nā ʻano hana conjugation kikoʻī kikoʻī, me ka hoʻohui ʻana i nā waikawa amino kūlohelohe, conjugation cysteine ​​​​engineed, ligation kōkua enzyme, glycan remodeling, a me ka hanauna o ka glycoconjugation.

Ke hoʻoholo nei i ka hoʻouna ʻana i ka lāʻau lapaʻau, hāʻawi ka XDC bioconjugation platform i nā hoʻolālā hoʻolālā holoʻokoʻa e hiki ai i ka hāʻawi ʻana i ka lāʻau lapaʻau i ka wahi i makemake ʻia o ka hana. ʻO ka lawe ʻana i nā conjugates antibody-drug, ke kumuhana maʻamau o nā XDCs, ma ke ʻano he laʻana, ua hoʻomohala ʻo BOC Sciences i nā ala kemika a enzymatic a i ʻole nā ​​hui pū ʻana o ia mea e hoʻololi pololei i nā waikawa amino kikoʻī e hana i nā ADC me ka hoʻouka lāʻau pololei a me nā pūnaewele pre-attachment.defipau a nānā ʻia.

No ka hoʻopuka ʻana i nā molekele i hoʻopaʻa ʻia, pono e noʻonoʻo nā loea BOC Science i nā mea e pili ana i ka pono, ka hiki ke komo i nā cell, ka pane ʻana o ka immune, ka nui mole, ka maʻalahi o ka synthesis, a me ke kumukūʻai. Ma hope o kēia mau alakaʻi, hiki i kāna kahua XDC ke hana i nā mea lawe lāʻau maikaʻi nui, ʻo ia hoʻi nā antibodies, nā ʻāpana antibody, nā peptides a me nā oligonucleotides. ʻO ka hāʻawi ʻana o RNAi He mea nui hoʻi ʻo ka XDC platform e hāʻawi i kahi ala hoʻohiki e hoʻomaʻemaʻe i ka hāʻawi ʻana i ka lāʻau intracellular i manaʻo ʻia ma o ka hoʻololi kemika o nā siRNA e hana i nā conjugates.

XDC bioconjugation kahua

ʻO kēia mau conjugates siRNA e like me GalNAc-siRNA conjugates a me antibody-siRNA conjugates e hōʻike ana i nā hiʻohiʻona i hoʻomaikaʻi ʻia i nā ʻōlelo o ka pharmacokinetics, uptake cellular, kikoʻī kikoʻī a me ka palekana. Ua hōʻike ʻo Kauka Carrie Taylor, ka waha ʻōlelo no BOC Science, i ke koʻikoʻi o kēia kahua bioconjugation XDC. Ua ʻōlelo ʻo ia: "Ke manaʻo nei kā mākou ʻenehana alakaʻi e hoʻoponopono i nā pilikia o nā ʻepekema i ke kahua o ka bioconjugation. Ma ka hōʻemi ʻana i nā mea ʻawaʻawa a me ka hoʻomaikaʻi ʻana i ka paʻa o ka hui ʻana, ke manaʻoʻiʻo nei mākou e kōkua nui ka XDC bioconjugation platform i ka hoʻomohala ʻana i nā biopharmaceuticals maikaʻi a me nā mea hana diagnostic. Me ka hoʻokuʻu ʻia ʻana o ka platform bioconjugation XDC kipi, hōʻoia hou ʻo BOC Science i kāna kūpaʻa i ka hoʻoulu ʻana i ka hana hou a me ka hoʻoikaika ʻana i nā mea noiʻi i kā lākou ʻimi ʻana i nā ʻike holomua i ka ʻepekema biomedical. "Ua mākaukau nā mea a pau e hoʻokō i nā pono bioconjugation like ʻole o nā mea noiʻi," i ʻōlelo ai ka ʻōlelo i nā ʻepekema.

ʻEpekema BOC

ʻO BOC Science he mea hoʻolako noiʻi (bio) kemika a me nā lawelawe bioconjugation. Ua kūpaʻa kāna hui o nā loea i ka hoʻolaha ʻana i ka holomua ʻepekema ma o ʻenehana hou a e hiki ai i nā mea noiʻi ke wehe i nā mea hou i ka hoʻomohala lāʻau.

Linna Green