Biognosys imapereka luso laukadaulo komanso kupita patsogolo kwasayansi kuti proteome igwiritsidwe ntchito pa kafukufuku wa sayansi ya moyo pa 2023 HUPO World Congress.

Kusanthula kwa data popanda malaibulale komanso mothandizidwa ndi kuphunzira pamakina ndi Spectronaut ^® 18 imapereka kuchuluka kwa mapuloteni otsogola m'makampani komanso kutulutsa kwa DIA proteinomics

Kafukufuku watsopano wogwirizira pogwiritsa ntchito nsanja za TrueDiscovery CRO ^® ndi TrueTarget ^® ikuwonetsa kulondola kwachulukidwe komanso kugwiritsidwa ntchito kwakukulu kwa ma mass spectrometry proteomics pakutulukira kwa biomarker ndi chitukuko cha mankhwala.

Biognosys iRT Kit ndiye mwala wapangodya wa kuwunika kwatsopano kwa nthawi yeniyeni kwa Bruker mkati mwa kusanthula kwa ProteoScape™ kwa zida za timsTOF.

Biognosys, woyambitsa komanso wopanga ma mass spectrometry (MS)-based proteomics solutions, lero alengeza kutenga nawo gawo mu Human Proteome Organisation (HUPO) World Congress kuyambira Seputembara 17 mpaka 21 ku Busan, South Korea.

Kutenga nawo mbali mu Congress

Pamsonkhano wa Technology Advances Lachiwiri, September 19, Dr. Lukas Reiter, Chief Technology Officer ku Biognosys, adzapereka "Bottom-up Proteomics pogwiritsa ntchito DIA" ulaliki wokhudzana ndi chisinthiko, zomwe zachitika posachedwa, ndi tsogolo la kupeza kopanda deta (DIA). ). mu MS-based proteinomics. Biognosys iperekanso zikwangwani khumi zowonetsa zatsopano zaukadaulo komanso zatsopano zasayansi ndi ntchito zake za proteomics, mapulogalamu ndi zida zofufuzira. Gulu la akatswiri asayansi a Biognosys liwonetsa ndikupereka ziwonetsero za pulogalamuyo pa booth no. 408.

Bruker, wothandizana naye wa Biognosys, ayambitsa malingaliro atsopano a nsanja ya timsTOF ndi pulogalamu ya Bruker ProteoScape™, kupanga mgwirizano ndi pulogalamu ya Spectronaut. ^® ndi Biognosys' iRT Kit kuti ipatse makasitomala luso lapamwamba la kukhulupirika kwambiri, ma proteinomic apamwamba kwambiri.

Ndemanga

"Ndili wokondwa kuwonetsa kupita patsogolo kwakukulu ndiukadaulo wa Biognosys's MS proteomics ndi mayankho omwe amatifikitsanso kufupi ndi kupanga proteome kukhala yothandiza pofufuza, kupanga mankhwala komanso kupanga zisankho zachipatala," adatero. Dr. Lukas Reiter . "Kupititsa patsogolo mapulogalamu athu mosalekeza ndi zida zotsimikiziridwa zimathandiza ogwiritsa ntchito zida zotsogola za MS kuti azitha kuchita bwino kwambiri, mopanda msoko kuti afufuze zakuya, zopanga zambiri, zopangananso zamkati. Ntchito zathu za CRO zimapereka makasitomala a biopharmaceutical ndi diagnostics mwatsatanetsatane komanso zidziwitso zomwe sizinachitikepo kuti apititse patsogolo kupezeka kwa biomarker ndi chitukuko cha mankhwala. ”

Spectronaut ^® 18: Kuzama kotsogola m'makampani, zokolola komanso magwiridwe antchito a DIA data analytics

Spectronaut 18, mtundu waposachedwa kwambiri wa pulogalamu yaposachedwa ya Biognosys, imapereka chiwongolero chowonjezereka cha zizindikiritso ndi kuchuluka kwa kachulukidwe, komanso zinthu zatsopano zomwe zimapangitsa kuti DIA proteomics ikhale yogwira ntchito komanso yowopsa. Ku HUPO, Biognosys ipereka zikwangwani zitatu zowunikira kugwiritsa ntchito kwamphamvu kwa Spectronaut 18 pakuwunika kwatsatanetsatane kwa proteome. Zatsopano zodziwika bwino zikuphatikiza kugwiritsa ntchito directDIA+ ™ kusanthula kwachangu, kopanda laibulale komanso deep learning ndi DeepQuant kuti apititse patsogolo kuchuluka kwa mapuloteni otsika kwambiri kudzera mu neural network kuti athetse kusokoneza kuchuluka kwa ma precursor.

TrueDiscovery ^® : kutsimikizika kotsimikizika kwa Kupezeka kwa biomarkers mu oncology ndi neuroscience

Biognosys ipereka zikwangwani zitatu zosonyeza kupezedwa kwa biomarker ndi kafukufuku wokhudza chitukuko cha mankhwala opangidwa ndi ogwira nawo ntchito olemekezeka, kuphatikiza Genmab, Johns Hopkins University School of Medicine, Stanford University, ndi University of Zurich. Maphunzirowa adagwiritsa ntchito nsanja ya Biognosys 'TrueDiscovery yopangira ma proteomics osakondera ndipo palimodzi akuwonetsa kulondola kwachulukidwe, kulimba, komanso kugwiritsidwa ntchito kwakukulu kwa MS proteomics pa kafukufuku wa oncology ndi neuroscience. Chojambula chachinayi chikuwunika ukadaulo ndi chilengedwe cha TrueDiscovery ndi nsanja ya Olink affinity ^{® Onani ndi Olink Proteomics AB ya plasma proteinomics.}

TrueTarget ^® : Kuchotsa chandamale kothandiza komanso kumangirira mapu pakupeza mankhwala

Pulatifomu ya TrueTarget ya Biognosys imagwiritsa ntchito ma proteolysis mass spectrometry (LiP-MS) kuti athandizire kuzindikira ndi kutsimikizira zomwe akufuna. Chojambula choyambirira, mothandizana ndi InterAx, chikuwonetsa kuthekera kwapadera kwa TrueTarget pothetsa chandamale cha mdani wa G protein-coupled receptor (GPCR), kupanga mapu a malo omwe amamangiriza ndikupereka zidziwitso zamachitidwe ake. Chojambula chachiwiri, chogwirizana ndi Samsara Therapeutics, chikuwonetsera momwe chandamale ikuwonongera ndi TrueTarget, yotsatiridwa ndi mbiri ya proteome yosakondera ndi TrueDiscovery, inathandiza kuzindikira bwino ndi kutsimikizira kwa mapuloteni omwe akuwunikira komanso kumvetsetsa bwino kwa machitidwe a zamoyo mu chitukuko chatsopano chamankhwala.

Biognosys ndi Bruker: Smooth workflows kwa dia-PASEF ^® ndi QC pa timsTOF

Kuti awonetsetse kuti MS ikugwira ntchito bwino, Bruker akuyambitsa TwinScape™, mapasa a digito papulatifomu ya timsTOF, yolumikizidwa ndi pulogalamu ya ProteoScape yothandizira kuwongolera kwanthawi yeniyeni (QC) ndi zida za Biognosys iRT. Ma peptide omwe ali mu kit iRT adakonzedwa bwino kuti azikhala okhazikika, okhudzidwa komanso osunga nthawi ndipo zida za iRT izi zitha kugwiritsidwa ntchito pakuwongolera machitidwe mu pulogalamu ya Bruker's ProteoScape proteomics. Biognosys Business Development Manager - Zamgulu, Dr. Sira Echevarria, adzapereka momwe Spectronaut amapereka bwino laibulale-free proteomic kusanthula kwa dia-PASEF ntchito directDIA+ pa Bruker a HUPO semina nkhomaliro Lachiwiri, September 19.

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